Medical Scientist Training Program

Degree Offered: M.D.-Ph.D.
Co-Director: William Geisler, M.D., MPH.
Co-Director: Talene Yacoubian, M.D., Ph.D
Director Title: Co-Directors of Medical Scientist Training Program
Phone: (205) 934-4092 or 934-0676
E-mail: mstp@uab.edu
Website: http://www.mstp.uab.edu

Overview

UAB’s outstanding research and clinical training programs provide a unique opportunity for students interested in careers in basic biomedical research. As a designated NIH Medical Scientist (M.D.-Ph.D.) Training Program (MSTP), students are admitted concurrently to the School of Medicine and the Graduate School in order to pursue both the M.D. degree and the Ph.D. degree. Ph.D. study in this program is available in the areas of biochemistry, structural, and stem cell biology; biomedical engineering; biostatistics; cancer biology; cell, molecular and developmental biology; epidemiology; genomics, and bioinformatics; health behavior; immunology; microbiology, neuroscience; nutrition sciences; pathobiology and molecular medicine; public health; sociology; and vision science.

Individuals admitted to this highly competitive program must have excellent undergraduate academic records and MCAT scores. In addition, successful applicants must have demonstrated their commitment to a career pathway as an investigator with active participation in an original research project prior to admission. Fellowship support, including a stipend and payment of tuition and fees, is provided to successful applicants.

In general, M.D.-Ph.D. students will first complete the basic science phase of the medical curriculum and the first-year core curriculum of their chosen Ph.D. discipline simultaneously. The second phase of study will focus on mentor selection, research path, and completion of a dissertation research project leading to the Ph.D. degree. The final phase of the program is a series of clinical rotations and an abbreviated set of acting internships to complete the M.D. degree. Normally, the program involves about 8 years for completion, depending on the time required to complete the dissertation research.

Interested applicants must complete the standard AMCAS application to the UAB School of Medicine and a short secondary application to the M.D.-Ph.D. program once the AMCAS application has been reviewed for consideration. More information is available at http://www.uab.edu/medicine/mstp/admissions/admissions-process

Students who have initiated study in the University of Alabama School of Medicine or the UAB Graduate School may also apply to the MD-PhD Program. Please contact the MSTP Directors for further information.

Biochemistry, Structural, and Stem Cell Biology (BSSB) Theme - MSTP/Arise

RequirementsHours
Module Courses (Recommended by Theme)
GBS 781Molecular Enzymology2-3
GBS 712Cellular and Molecular Aspects of Developmental Biology2-3
GBS 782Molecular Genetics2-3
GBS 784Stem Cell Biology2-3
Theme Required Course
GBSC 742GBS Student Theme Meeting Course1
GBS Required Courses
GRD 717Principles of Scientific Integrity3
One Grant Writing/Scientific Writing 21
Biostatistics 32
Journal Clubs 43
Three Advanced Courses 49
MSTP/ARISE Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours53-57

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Cancer Biology (CANB) Theme - MSTP/Arise

RequirementsHours
Module Courses
GBS 710Cell Signaling2-3
GBS 720Genomic Structure and Function2-3
GBS 769Carcinogenesis2-3
GBS 774Cancer Immunology2-3
Theme Required Courses
GBS 770Pathobiology of Cancer2-3
GBS 777Cancer Biology Seminar1
GBS Required Courses
GRD 717Principles of Scientific Integrity3
Grant Writing/Scientific Writing 12
Biostatistics 23
Journal Clubs 31
Advanced Courses 49
MSTP/Arise Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours55-60

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Cell, Molecular & Developmental Biology (CMDB) Theme - MSTP/Arise

RequirementsHours
Module Courses
GBS 710Cell Signaling2-3
GBS 712Cellular and Molecular Aspects of Developmental Biology2-3
GBS 714Developmental Neuroscience2-3
GBS 784Stem Cell Biology2-3
Theme Required Courses
GBS 717Methods and Scientific Logic1
GBS 792CMDB Seminar1
GBS Required Courses
GRD 717Principles of Scientific Integrity3
Grant Writing/Scientific Writing 12
Biostatistics 23
Journal Clubs 31
Advanced Courses 49
MSTP/ARISE Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours54-58

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Genetics, Genomics and Bioinformatics (GGB) Theme - MSTP/Arise

RequirementsHours
Module Courses
GBS 724Principles of Human Genetics2-3
GBS 720Genomic Structure and Function2-3
GBS 722Bioinformatics2-3
GBSC 718Epigenetics2-3
Theme Required Courses
GBS 717Methods and Scientific Logic1
GBSC 742GBS Student Theme Meeting Course1
GBS Required Courses
GRD 717Principles of Scientific Integrity3
Grant Writing/Scientific Writing 12
Biostatistics 23
Journal Clubs 31
Advanced Courses 49
MSTP/Arise Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours54-58

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Immunology (IMM) Theme - MSTP/Arise

RequirementsHours
Module Courses
GBS 740AIntroduction to Immunology Part 12-3
GBS 740BIntroduction to Immunology Part 22-3
GBS 744Mucosal Immunology2-3
GBS 741Lymphocyte Biology2-3
Theme Required Courses
GBS 742Dendritic Cell Biology3
GBS Required Courses
GRD 717Principles of Scientific Integrity3
Grant Writing/Scientific Writing 12
Biostatistics 23
Journal Clubs 31
Advanced Courses 49
MSTP/Arise Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours55-59

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Microbiology (MIC) Theme - MSTP/Arise

RequirementsHours
Module Courses
GBS 760Prokaryotic Genetics and Molecular Biology2-3
GBS 764Structural Biology for Micro2-3
GBS 763Microbial Pathogenesis2-3
GBS 762Virology2-3
Theme Required Courses
GBS 742Dendritic Cell Biology3
GRD 717Principles of Scientific Integrity3
Grant Writing/Scientific Writing 12
Biostatistics 23
Journal Clubs 31
Advanced Courses 49
MSTP/Arise Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours55-59

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Neuroscience (NESC) Theme- MSTP/ARISE

RequirementsHours
Module Courses (Recommended By Theme)
GBS 747Special Topics (Neuroanatomy)2
GBSC 729Cell Neurophysiology2
GBS 714Developmental Neuroscience2
GBSC 727Neuro Systems2
Theme Required Course
GBS 737Neuro Student Summer Seminar Series1
NBL 703Nuerobiology Seminar Series1
GBS Required Course
GRD 717Principles of Scientific Integrity3
Grant-writing/Scientific-writing 12
Biostatistics 23
Jornal Clubs 31
Three Advanced Courses 49
MSTP/ARISE Required Course
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research Hours 724
Total Hours54
  • Students must be registered for 9 hours each semester. Any hours over must be approved by the MSTP/ARISE Director.
  • Must obtain permission of Thesis Mentor, Theme Director, and MSTP/ARISE Director to register for Career Development courses (e.g., GRD and CIRTL)
  • Students must be admitted to candidacy for a minimum of 1 year before the thesis defense

Additional MSTP/ARISE Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP Requirement)
  • Committee Meetings held every 6 months

Additional Theme Requirements:

  • Publications: At least one published first author paper & one submission to a journal. Co-author papers are encouraged.
  • Presentations: At least two presentations at a national or international scientific meeting (poster and/or oral).

Pathobiology and Molecular Medicine (PBMM) Theme - MSTP/Arise

RequirementsHours
Module Courses
GBS 750Nerves, Muscles and Bones2-3
GBS 751Heart, Lung, and Kidney2-3
GBS 752GI, Endocrine, and Immune System2-3
GBS 753Pharmacology, Toxicology, and Molecular Medicine2-3
Theme Required Courses
GBS 742Dendritic Cell Biology3
GBS Required Courses
GRD 717Principles of Scientific Integrity3
Grant Writing/Scientific Writing 12
Biostatistics 23
Journal Clubs 31
Advanced Courses 49
MSTP/Arise Required Courses
MSTP 794Translational Research Seminar 51
MSTP 795Continuing Clinical Education 61
Research 724
Total Hours55-59

Please note:

  • Seminars are recommended to attend, but registration is not required.
  • Students must be registered for 9 hours each semester.  Any hours over 9 must be approved by the MSTP/Arise Director. 
  • Career development course registration (GRD, CIRTL) requires the permission of the Thesis Mentor, Theme Director, and MSTP/ARISE Director.
  • Students must be admitted to candidacy for a minimum of one year before the thesis defense.

Additional MSTP/Arise Requirements:

  • Submission of F30/F31 on or before April of GS2 Year (MSTP requirement).
  • Committee meetings held every six months.

Additional Theme Requirements:

  • Publications: At least one published paper.
  • Presentations: At least one presentation at a national or international scientific meeting.

Courses

MSTP 794. Translational Research Seminar. 1 Hour.

The CAMS Translational Research Seminar series, required fall, spring and summer semesters, invites UAB faculty (PhD, MD, MD-PhD or MPH) who are conducting translational research to present their work to students in the MSTP. The goal of the presentation is three fold: (a) to inform students about the career path of the investigator, (b) to provide them with information regarding the initiation and conduct of translational research, and (c) to expose students to current developments in basic and clinical research. There are two to three sessions each year in which panels or round tables discuss topics, including mentor selection, preparation for residency, residency selection, and the overall UAB MSTP experience. Lecturers give a 45-minute presentation followed by a 15-minute question and answer session. This course is open only to MD-PhD students.

MSTP 795. Continuing Clinical Education. 1 Hour.

This course is designed to maintain clinical skills and knowledge during students’ dissertation research years. MSTP students will take the course every fall semester and spring semester during their PhD dissertation phase. Each semester, students will be required to complete seven course components. Some components serve to maintain clinical skills and includes students conducting a resident-supervised clinical encounter as well as completing one half day of shadowing. Other components serve to maintain or bolster clinical knowledge and include students attending case conferences and/or participating in simulation sessions. This course is open only to MD-PhD students.

MSTP 796. Anatomy Lab TA Opportunity. 1 Hour.

From 23 TOTAL dissections between the MS1 and MS2 years, students choose any 6 dissections to teach depending on their availability. Overview: MS4 students will serve as Anatomy Teaching Associates for MS1 and MS2 students during scheduled lab times to make preclinical training more robust and clinically relevant. Course benefits for MS4 students: - Small-group anatomy training aimed to improve knowledge of anatomy & dissection skills. - Teaching & mentoring experience of students with less clinical experience. - Flexible schedule: Preferred dissections may be changed up to 1 week before the preclinical scheduled lab time. Format: - Students will attend a 1-hour orientation session addressing effective teaching techniques in August of the entering year (accommodation for absence can be made on a case-by-case basis). - The week prior to their chosen dissections, students will receive 2 hours of small group training in SOM lab under the directions of trained UAB Anatomist and Course Director Dr. Resuehr. During this training, students will perform the relevant cadaveric dissection which will be saved for demonstration during the preclinical lab. -TAs will be assigned to a group of preclinical students during their scheduled lab time to help answer questions. Particular emphasis will be placed on providing preclinical students with clinical correlates. Learning Objectives: - Dissect and identify all associated structures of their chosen dissections emphasizing the relation of structures to each other and common pathologies. - Understand common anatomical variations (if applicable). - Understand anatomically relevant information pertaining to clinical procedures. - Understand geriatric changes. - Mentor and teach students with less experience.

MSTP 798. MSTP Non-Dissertation Hours. 1-8 Hour.

Laboratory research pre-qualification. Only open to MSTP students.

MSTP 799. MSTP Dissertation Hours. 1-8 Hour.

Dissertation research. Only open to MSTP students.
Prerequisites: GAC Z