Medical Scientist Training Program

Degree Offered: M.D.-Ph.D.
Co-Director: William Geisler, M.D., MPH.
Co-Director: Talene Yacoubian, M.D., Ph.D
Director Title: Co-Directors of Medical Scientist Training Program
Phone: (205) 934-4092 or 934-0676
E-mail: mstp@uab.edu
Website: http://www.mstp.uab.edu

Overview

UAB’s outstanding research and clinical training programs provide a unique opportunity for students interested in careers in basic biomedical research. As a designated NIH Medical Scientist (M.D.-Ph.D.) Training Program (MSTP), students are admitted concurrently to the School of Medicine and the Graduate School in order to pursue both the M.D. degree and the Ph.D. degree. Ph.D. study in this program is available in the areas of biochemistry, structural, and stem cell biology; biomedical engineering; biostatistics; cancer biology; cell, molecular and developmental biology; epidemiology; genomics, and bioinformatics; health behavior; immunology; microbiology, neuroscience; nutrition sciences; pathobiology and molecular medicine; public health; sociology; and vision science.

Individuals admitted to this highly competitive program must have excellent undergraduate academic records and MCAT scores. In addition, successful applicants must have demonstrated their commitment to a career pathway as an investigator with active participation in an original research project prior to admission. Fellowship support, including a stipend and payment of tuition and fees, is provided to successful applicants.

In general, M.D.-Ph.D. students will first complete the basic science phase of the medical curriculum and the first-year core curriculum of their chosen Ph.D. discipline simultaneously. The second phase of study will focus on mentor selection, research path, and completion of a dissertation research project leading to the Ph.D. degree. The final phase of the program is a series of clinical rotations and an abbreviated set of acting internships to complete the M.D. degree. Normally, the program involves about 8 years for completion, depending on the time required to complete the dissertation research.

Interested applicants must complete the standard AMCAS application to the UAB School of Medicine and a short secondary application to the M.D.-Ph.D. program once the AMCAS application has been reviewed for consideration. More information is available at https://www.uab.edu/medicine/mstp/admissions

Students who have initiated study in the University of Alabama School of Medicine or the UAB Graduate School may also apply to the MD-PhD Program. Please contact the MSTP Directors for further information.

Biochemistry & Structural Biology (BSB) Theme - MSTP/ARISE

RequirementsHours
Module Courses 18
Theme Required Course6
GBS Student Theme Meeting Course 2
GBS Required Courses23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 3
Biostatistics 4
Journal Clubs 5
Three Advanced Courses 6
MSTP/ARISE Required Courses39
Translational Research Seminar 7
Continuing Clinical Education 8
Research 9
Total Hours76

Cancer Biology (CANB) Theme - MSTP/ARISE

RequirementsHours
Module Courses 8
Cell Signaling
Carcinogenesis
Pathobiology of Cancer
Cancer Immunology
Theme Required Courses6
Cancer Biology Seminar 1
GBS Required Courses23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 2
Biostatistics 3
Journal Clubs 4
Three Advanced Courses 5
MSTP/ARISE Required Courses39
Translational Research Seminar 6
Continuing Clinical Education 7
Research 8
Total Hours76

Cell, Molecular & Developmental Biology (CMDB) Theme - MSTP/ARISE

RequirementsHours
Module Courses 18
Theme Required Courses7
Methods and Scientific Logic
CMDB Seminar 2
GBS Required Courses23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 3
Biostatistics 4
Journal Clubs 5
Three Advanced Courses 6
MSTP/ARISE Required Courses39
Translational Research Seminar 7
Continuing Clinical Education 8
Research 9
Total Hours77

Genetics, Genomics and Bioinformatics (GGB) Theme - MSTP/ARISE

RequirementsHours
Module Courses 18
Theme Required Courses7
Methods and Scientific Logic
GBS Student Theme Meeting Course 2
GBS Required Courses23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 3
Biostatistics 4
Journal Clubs 5
Three Advanced Courses 6
MSTP/ARISE Required Courses39
Translational Research Seminar 7
Continuing Clinical Education 8
Research 9
Total Hours77

Immunology (IMM) Theme - MSTP/ARISE

RequirementsHours
Module Courses 8
Introduction to Immunology Part 1
Introduction to Immunology Part 2
Mucosal Immunology
Lymphocyte Biology
Theme Required Courses6
GBS Student Theme Meeting Course 1
GBS Required Courses23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 2
Biostatistics 3
Journal Clubs 4
Three Advanced Courses 5
MSTP/ARISE Required Courses39
Translational Research Seminar 6
Continuing Clinical Education 7
Research 8
Total Hours76

Microbiology (MIC) Theme - MSTP/ARISE

RequirementsHours
Module Courses 8
Bacterial Genetics and Physiology
Virology
Introduction to Structural Biology Methods
Microbial Pathogenesis
Theme Required Courses8
Communicating Science: Reading, Writing and Presentation
GBS Student Theme Meeting Course 1
GBS Required Courses23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 2
Biostatistics 3
Journal Clubs 4
Advanced Courses 5
MSTP/ARISE Required Courses39
Translational Research Seminar 6
Continuing Clinical Education 7
Research 8
Total Hours78

Neuroscience (NEURO) Theme - MSTP/ARISE

RequirementsHours
Module Courses8
Neuroanatomy
Cell Neurophysiology
Developmental Neuroscience
Neuro Systems
Theme Required Courses9
Neuro Student Summer Seminar Series 1
Nuerobiology Seminar Series 2
GBS Required Course23
Principles of Scientific Integrity
Grant-Writing/Scientific Communication 3
Biostatistics 4
Journal Clubs 5
Three Advanced Courses 6
MSTP/ARISE Required Course39
Translational Research Seminar 7
Continuing Clinical Education 8
Research Hours 9
Total Hours79

Pathobiology, Pharmacology, & Physiology (P3) Theme - MSTP/ARISE

RequirementsHours
Module Courses 8
Intro to Physiology
Intro to Physiology II
Intro to Pathobiology
Intro to Pharmacology & Toxicology
Theme Required Courses6
GBS Student Theme Meeting Course 1
GBS Required Courses23
Principles of Scientific Integrity
Grant Writing/Scientific Writing 2
Biostatistics 3
Journal Clubs 4
Advanced Courses 5
MSTP/Arise Required Courses39
Translational Research Seminar 6
Continuing Clinical Education 7
Research 8
Total Hours76

Courses

MSTP 793. Basic Research Forum. 1 Hour.

This course is for entering MD-PHD students to meet the GBS Core-Course requirements. The following list consists of desirable competencies for enrolled MD-PHD students to achieve while in this course: (a) Learn fundamental topics in biomedical research that will not be covered in SOM courses; (b) Fill gaps in curriculum between GBS707/709; and (c) Introduce topics that may be of interest for future lab rotations.

MSTP 794. Translational Research Seminar. 1 Hour.

The CAMS Translational Research Seminar series, required fall, spring and summer semesters, invites UAB faculty (PhD, MD, MD-PhD or MPH) who are conducting translational research to present their work to students in the MSTP. The goal of the presentation is three fold: (a) to inform students about the career path of the investigator, (b) to provide them with information regarding the initiation and conduct of translational research, and (c) to expose students to current developments in basic and clinical research. There are two to three sessions each year in which panels or round tables discuss topics, including mentor selection, preparation for residency, residency selection, and the overall UAB MSTP experience. Lecturers give a 45-minute presentation followed by a 15-minute question and answer session. This course is open only to MD-PhD students.

MSTP 795. Continuing Clinical Education. 1 Hour.

This course is designed to maintain clinical skills and knowledge during students’ dissertation research years. MSTP students will take the course every fall semester and spring semester during their PhD dissertation phase. Each semester, students will be required to complete seven course components. Some components serve to maintain clinical skills and includes students conducting a resident-supervised clinical encounter as well as completing one half day of shadowing. Other components serve to maintain or bolster clinical knowledge and include students attending case conferences and/or participating in simulation sessions. This course is open only to MD-PhD students.

MSTP 796. Anatomy Lab TA Opportunity. 1 Hour.

From 23 TOTAL dissections between the MS1 and MS2 years, students choose any 6 dissections to teach depending on their availability. Overview: MS4 students will serve as Anatomy Teaching Associates for MS1 and MS2 students during scheduled lab times to make preclinical training more robust and clinically relevant. Course benefits for MS4 students: - Small-group anatomy training aimed to improve knowledge of anatomy & dissection skills. - Teaching & mentoring experience of students with less clinical experience. - Flexible schedule: Preferred dissections may be changed up to 1 week before the preclinical scheduled lab time. Format: - Students will attend a 1-hour orientation session addressing effective teaching techniques in August of the entering year (accommodation for absence can be made on a case-by-case basis). - The week prior to their chosen dissections, students will receive 2 hours of small group training in SOM lab under the directions of trained UAB Anatomist and Course Director Dr. Resuehr. During this training, students will perform the relevant cadaveric dissection which will be saved for demonstration during the preclinical lab. -TAs will be assigned to a group of preclinical students during their scheduled lab time to help answer questions. Particular emphasis will be placed on providing preclinical students with clinical correlates. Learning Objectives: - Dissect and identify all associated structures of their chosen dissections emphasizing the relation of structures to each other and common pathologies. - Understand common anatomical variations (if applicable). - Understand anatomically relevant information pertaining to clinical procedures. - Understand geriatric changes. - Mentor and teach students with less experience.

MSTP 798. MSTP Non-Dissertation Hours. 1-8 Hour.

Laboratory research pre-qualification. Only open to MSTP students.

MSTP 799. MSTP Dissertation Hours. 1-8 Hour.

Dissertation research. Only open to MSTP students.
Prerequisites: GAC Z